The Relation of Circulating CC16 to Lung Function Growth, Decline, and Development of COPD Across the Lifespan
Background Low serum levels of the anti-inflammatory club cell secretory protein (CC16) have been associated with an accelerated FEV1 decline in COPD. Whether low circulating CC16 precedes lung function deficits and incidence of COPD in the general population is unknown. Methods We used longitudinal data from adults who were COPD-free at baseline from the population-based […]